Hypercorticolism due to Thymic tumour and secondary antibody deficiency

Reference: Sarcevic, J., Berger, C. T., Cavelti-Weder, C., & Trendelenburg, M. (2020). Case report-Secondary Antibody Deficiency due to Endogenous Hypercortisolism. Frontiers in Immunology, 11, 1435.

Take Home Message: Authors report a young adult with ACTH producing thymic tumour with elevated cortisol levels with extensive immunological work up that replicated the effect of corticosteroid therapy leading to a transient CVID like phenotype