HLH

Mutation spectrum of genetic variants in Hemophagocytic lymphohistiocytosis

HLH / By

Reference: Vanessa Gadoury-Levesque, Lei Dong, Rui Su, Jianjun Chen, Kejian Zhang, Kimberly A. Risma, Rebecca A. Marsh, Miao Sun; Frequency and spectrum of disease-causing variants in 1892 patients with suspected genetic HLH disorders. Blood Adv 2020; 4 (12): 2578–2594. Journal: Blood Advances Summary: 1892 samples were retrospectively analysed, 197 samples had pathogenic or likely pathogenic variants in …

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Easy Blood based Prognostic markers in Secondary HLH

HLH, secondary HLH / By

Reference: Huang, J., Yin, G., Duan, L. et al. Prognostic Value of Blood-Based Inflammatory Biomarkers in Secondary Hemophagocytic Lymphohistiocytosis. J Clin Immunol (2020). Journal: Journal of Clinical Immunology Summary: 1. Study intends to check utility of easily available blood ratios and other inflammatory markers in Secondary HLH(sHLH) 2.Malignancy was commonest cause with nearly half of patients …

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